External Conflict: As young men the doctors struggle to overcome adversity, while living in the worst neighborhoods in Newark, NJ
Internal Conflict: The boys often struggle with perseverance while engaging in their college/medical school studies. They often question if being a doctor is what they really want to be their career.
''But I don't plan to fail'' - quote from Dr. George Jenkins who was always persistent on his goal of going to college.
""It just seems easier to give up. No One from our neighborhood ever makes it out. You're either gunned down, or arrested, or you get some crazy disease. Everybody fails."" - quote from Dr. Sampson Davis, who multiple times during the book considered giving up.