Prader-Willi Syndrome

What is it?

• A genetic multisystem disease
• Chromosome 15
• Other terms used
• Prevalence

History

• Named after Andrea, Alexis, and Heinrich
• Phases I and II (60's)
• Further research (70's, 80's and 90's)

Signs and symptoms: prenatal-Infancy

• Hypotonia
• Lethargy
• Poor response to stimuli
• Weak cry
• Poor reflexes
• Poor sucking ability
• feeding difficulties

childhood features (2-18 years old)

• Global developmental delay
• Stort stature
• Hyperphagia
• Obesity
• Hypogonadism/hypogenitalism
• Small hands and feet
• Obsession with food
• Behavior problems

Clinical Characteristics of Nutritional Phases

Clinical Characteristics of Nutritional Phases

Clinical Characteristics of Nutritional Phases

Clinical Characteristics of Nutritional Phases

HOw can teachers help students with PWI?

• Preschool and Elementary students
• Middle and High School students
• Observe and evaluate often
• Teach the teachers!
• Restriction of access to food
• Create community understanding

References

• Angulo, M. A., et al. “Prader-Willi Syndrome: a Review of Clinical, Genetic, and Endocrine Findings.” Journal of Endocrinological Investigation, vol. 38, no. 12, Dec. 2015, pp. 1249–1263., link.springer.com/article/10.1007/s40618-015-0312-9#enumeration.
• Chedd, Naomi, et al. “Educational Considerations for Children with Prader-Willi Syndrome.” Pwsausa.org, www.pwsausa.org/wp-content/uploads/2016/12/Module-5-prereading-Educational-....

References

• “History & Prevalence.” History and Prevalence of Prader-Willi Syndrome, www.findresources.co.uk/the-syndromes/prader-willi/history-prevalence.
• “Prader Willi Syndrome.” NORD (National Organization for Rare Disorders), 2015, rarediseases.org/rare-diseases/prader-willi-syndrome/.

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