This species has declined in numbers by over 80% over the past decade, most likely due to chytridiomycosis. It is also threatened by collection for local zoos and hotels, illegal pet trading, deforestation, and habitat alteration by logging and farming
Chytridiomycosis is an infectious disease of amphibians, caused by the chytrid Batrachochytrium dendrobatidis, a nonhyphal zoosporic fungus.
A trade ban has prohibited removing it from its habitat, reducing collection and allowing some revival of the natural population. Unsurprisingly, it also faces habitat destruction as another threat, but domestic gardens and greenhouses provide a safety net against total extinction and serve alongside the trade ban as the main measures preventing the extinction of Euphorbia obesa.
eastern and central Africa, and currently can be found in reserves in countries such as Kenya, Tanzania, Cameroon, South Africa, Namibia, Zimbabwe, Malawi, Swaziland, and Angola.
deserts, grasslands and woodlands, shrublands, and savannahs.
There are Unfenced reserves which are under heavy protection. Steps have also been taken to take down the illegal trade of rhinoceros horns from Africa to other areas worldwide.