Trimethylaminuria

STRUCTURE AND FUNCTION OF DNA

SYMPTOMS

• Nasty odor - usually smells like fish, eggs, or urine
• Usually worse when stressed
• Can cause social and psychological problems
• Liver failure
• Increased blood pressure
• Severe depression

Trimethylaminuria is inherited, and is received when both parents have a missing FMO3 gene. Valine is turned into Leucine

DNA: ATG CAC TTC
Original Strand RNA Codon:
UAC GUG AAG
Tyrosine Valine Lysine

Mutated DNA: ATG TAC TTC
RNA Sequence:

UAG AUG AAG
Tyrosine Leucine Lysine

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