Blood Groups & Blood Transfusions
Published on Mar 16, 2016
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PRESENTATION OUTLINE
Blood Groups
Determined by genetically controlled, polymorphic, antigenic components of the RBC membrane.
Some blood group systems are highly complex, with many alleles defined as a locus.
Others blood groups consist of a single defined antigen.
Blood groups systems, in general, are independent of one another, and their inheritance conforms to Mendelian dominance.
POLYMORPHIC BLOOD GROUPS
An animal usually inherits one allele from each parent, expressing no more than 2 blood group antigens of a system.
Exception:
Cattle
Multiple alleles (phenogroups) are inherited.
Individuals don't have antibodies against antigens UNLESS they have been induced by transfusion, pregnancy, or immunization.
BLOOD TRANSFUSIONS
With random blood transfusions in dogs, there is a 30% - 40% chance of sensitization of the recipient, primarily to blood group antigen DEA 1
But risk is also present for development of antibody to any other antigen lacked by the recipient.
BLOOD GROUP SYSTEMS
The number of major recognized blood group systems varies among domestic species.
Cattle being the most complex, cats being the simplest.
Animal blood groups are typed to aid in the matching of donors and recipients.
In most cases, DNA testing has replaced blood typing for paternity testing.
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BY: AMANDA & DEVIN
CITED SOURCE: THE MERCK MANUAL
