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Johns Hopkins University Hospital & Neuropace

Published on Nov 22, 2015

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1.

Epilepsy Treatment

Organizational Effectiveness
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2.

Agenda

  • Epilepsy Quiz
  • Facts about Epilepsy
  • Research Hospitals
  • Pharmaceutical Companies
  • Universities
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3.

Epilepsy Quiz

Photo by Leo Reynolds
4.

epilepsy facts

  • 1 in 26 Americans will develop epilepsy in their lifetime
  • Approximately 65 million people worldwide live with epilepsy
  • In 2/3 of patients diagnosed with epilepsy, the cause is unknown
  • Affects more people than MS, CP, muscular dystrophy and Parkinsons combined
  • Fewer federal dollars per patient than EACH of these individually.
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5.

Epilepsy facts continued

  • Up to 50k deaths occur annually from epilepsy
  • SUDEP accounts for 34% of all deaths in children
  • 440k soldiers have experienced TBI and more than 100k will develop PTE
  • Epilepsy costs the US $15.5 B annually.  
  • (retreived from http://www.cureepilepsy.org/aboutepilepsy/facts.asp)
Photo by sickmouthy
6.

Medication Types

  • Tegretol/Carbetrol
  • Keppra
  • Onfi
  • Dilantin
  • Topamax
Photo by Curtis Gregory Perry
7.

Organizational Effectiveness at

Pharmaceutical Companies
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8.

Companies making Epilepsy drugs

  • Janssen Pharmaceuticals (Topamax)
  • UCB (Keppra)
  • Lundbeck (Onfi)
  • Novartis (Tegretol)
  • Shire (Carbetrol)
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9.

Company purpose

  • Contributing to the health of the community
  • Bottom line
  • Charitable contributions (e.g. Seizure Response Dogs)
  • Research & Development
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10.

Janssen Pharmaceuticals

Importance of Medication Management
http://www.janssenpharmaceuticalsinc.com/care-coordination/transitions-of-c...
Photo by garryknight
11.

What did Janssen Pharmaceuticals Do Right?

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12.

Organizational Effectiveness at

Research Hospitals
Photo by Doug Letterman
13.

Johns Hopkins University Hospital

  • #1 in Neurology and Neurosurgery - US News & World Report
  • #1 as a hospital for 21 years running - US News & World Report
  • One of the first & leading research hospitals looking into dietary therapy
  • Medications, VNS, Dietary therapy, & Surgery are all used
Photo by e-MagineArt.com
14.

The Patient Experience

http://www.hopkinsmedicine.org/neurology_neurosurgery/news/videos/patient_e...
Photo by markhillary
15.

What Are the Things Johns Hopkins did Right?

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16.

What happens when Pharmaceutical companies

& Research Hospitals Collide???
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17.

Single vs Double Blind studies

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18.

Blind Studies

  • Refers to the level of impartiality of the study
  • Single blind studies - only participants do not know
  • Double blind studies - both participants & researchers do not know
  • Double blind studies can remove the bias from studies
  • Sometimes Single blind is preferred as it is necessary
Photo by Visentico / Sento
19.

Single Blind Experiment

Coffee Taste Test
Photo by "The Wanderer's Eye Photography"
20.

What did you notice?

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