FSH & LH

FSH

• Produced in the anterior pituitary gland
• Target organ for females: follicles in ovaries
• Target organ for males: seminiferous tubules
• Secretion regulated by hypothalamus since it controls the anterior pituitary gland

FSH

• Function in females: stimulates follicles to produce mature eggs and secrete estradiol
• Function in males: stimulates seminiferous tubules to produce spermatozoa

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LH

• Produced in anterior pituitary gland
• Target in females: follicles in ovaries
• Target in males: testes
• Regulated by hypothalamus

LH

• Function in males is to produce testosterone
• Function in females is to stimulate a follicle each month to release a mature egg. It stimulates the secretion of estradiol and progesterone

HYPO-SECRETION OF FSH & LH

• Diseases of hyposecretion are similar for both
• Hyposecretion in females causes infertility, lack of ovulation, miscarriages, low levels of estradiol, lack of sexual development
• Hyposecretion in males causes sterility and enlarged male breasts( gynecomastia) due to imbalances of testosterone production

HYPERSECRETION OF FSH & LH

• Precocious puberty: premature ovulation and menstruation in women. Hyperproduction of sperm in males.

WHAT CAUSES DISEASES AND HOW TO FIX

• Caused by adenoma in the anterior pituitary gland or malfunctioning in hypothalamus
• Treated by removing adenoma in anterior pituitary gland

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