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CUTANEOUS T-CELL LYMPHOMA

Published on Nov 20, 2015

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PRESENTATION OUTLINE

CUTANEOUS T-CELL LYMPHOMA

A CANCER OF LYMPHOCYTES

WHAT IS CTCL?

  • Cancer of the white blood cells that primarily involve the skin
  • It is the most common type of cutaneous lymphoma
  • Typically presents with red, scaly patches or thickened plaques of skin.
  • Often mimics eczema or chronic dermatitis
  • Progression may accompany tumor formation, ulceration and exfoliation
Photo by NIAID

WHAT IS THE LARGEST ORGAN OF THE BODY?

Photo by kevin dooley

THE DIAGNOSIS

  • Usually made by Dermatologist
  • Physical examination and history
  • Blood tests
  • Skin biopsy/lymph node biopsy
  • Series of imaging (CT, MRI, PET)

THE STAGES

  • Stage I: Less than 10% of skin affected w/ raised red patches on skin
  • Stage II: Same as above plus lymph nodes are enlarged but not cancerous
  • Stage III: More than 80% of skin is erythromeric. Lymph nodes may or may not be affected.
  • Stage IV: Now malignant and metastisized to other organs
Photo by pareeerica

TREATMENT

  • Topical chemotherapy
  • Local radiation
  • Methotrexate
  • Photopheresis
  • Phototherapy

ADVANCED THERAPY

  • Radiation
  • Chemotherapy
  • Combination chemo is last resort
Photo by Phil and Pam

EFFECTS OF TREATMENTS

  • Fatigue
  • Nausea
  • Fever
  • Chills
  • Dizziness

SYNOPSIS

  • T-cell lymphoma accounts for 15% of NHL's
  • Most CTCL's are indolent- treatable, not curable and not life-threatening.
  • Red, scaly rash that mimic eczema or chronic dermatitis
  • Typically found by a Dermatologist
Photo by -Dreamflow-