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Coffee to stay awake; for everything else there's KETAMINE

Published on Sep 10, 2019

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PRESENTATION OUTLINE

When the Going Gets Weird

Ian Mitchell, MD, FRCP
Photo by robnguyen01

No Disclosures

Photo by xcorex

Vancouver

Ketamine for abscess drainage in IDU

Abu Dhabi

Ketamine for pediatric laceration repair

Untitled Slide

  • Associate Professor of Emergency Medicine, UBC
  • Staff Physician, Royal Inland Hospital, Kamloops
  • Scholar, Kamloops Family Medicine Residency Program
  • Cannabis Clinician & Researcher

Procedural Sedation

Subdissociative Dosing

Acute Pain: 10-20 mg iv over 10 min then 10-20 mg/hr infusion

Ketamine for Kids

  • 4 mg/kg intramuscular
  • 1 mg/kg intravenous
  • 1-10 mg/kg intranasal

Pain-K Trial

Prehospital ketamine

Cannabis Hyperemesis Syndrome

Ketamine 15 mg/Chlorpromazine 12.5 mg
Photo by david_jup

Extreme Ketamine

Burning Man

Ketamine Dart - 5 mg/kg im for agitation
Photo by Trey Ratcliff

DSI

1-1.5 mg/kg slow push
Photo by AllieKF

Status Epilepticus

Photo by PNASH

Asthma

0.3-0.5 mg/kg iv over 2 min then same over 30 min
Photo by PNASH

Acute Suicide Treatment

Antidepressant dosage: 0.5-1 mg/kg iv
synapse growth

Ideal Patient?


Depressed, asthmatic child with broken arm.

Photo by NIH-NCATS

Contraindications

Photo by C Drying

Increased IOP

MYTH!

Increased ICP

MYTH!

Psychosis

Cardiac

Photo by Popfossa

Complications

Vomiting
Photo by Steve E.

Laryngospasm

  • children
  • break with 2 person BVM
  • Larsen maneuver
Laryngospasm in 0.3% of pediatric
Photo by iDanSimpson

Ketamine Emergence Phenomenon

Solution: More Ketamine
Photo by Chen Yuchun

Other Issues

Coadministration

Propofol + Ketamine = Ketofol

Pre-experience Counselling

vs "It's going to get weird"
Photo by gl/gc?int=25

What is the Maximum Dose?

J Emerg Med Sept 24, 2019

Opiate Induced Hyperalgesia

NMDA mediated

Education Needed

  • increase awareness of set and setting.
  • Standardize dosing and treatment

My Questions

  • Separate pharmacology from psychotherapy
  • Do some benefits require psychedelic dosing?
  • Will coadministered drugs affect results?

Coffee to stay awake; for everything else there's KETAMINE


@travels2little

Photo by Jason Dent