Adrenaline
Published on Oct 07, 2022
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PRESENTATION OUTLINE
Indications
- anaphylaxis
- severe asthma
- moderate to severe stridor
- clinically significant epistaxis
- clinically significant bleeding from a wound
EMTs use adrenaline to treat swollen airways and to stop bleeding.
Photo by yoppy
Doses
- 0.5 mg IM for anaphylaxis
- 0.5 mg IM for severe asthma
- 5mg neb for stridor (moderate to severe respiratory distress)
Adrenaline is supplied in ampoules containing 1mg in 1 ml.
Therefore 5 ampoules are used to treat severe stridor.
Therefore 5 ampoules are used to treat severe stridor.
Photo by J. Bell
Doses
- Each mg diluted to total of 10 ml using 0.9% saline. IN for epistaxis
- Each mg diluted to total of 10 ml using 0.9% saline. Topical for bleeding wound
This solution is 1:10,000 and contains 0.1 mg/ml. Administer the appropriate dose into each bleeding nostril using a mucosal atomising device, in addition to direct pressure.
Photo by lilartsy
Alpha 1 stimulation causes smooth muscle contraction, vasoconstriction of blood vessels and stimulation of glycogenolysis and gluconeogenesis.
Photo by Double--M
Beta 1 stimulation causes an increase in inotropy (cardiac contractility), an increase in chronotropy (heart rate) and an increase in dromotropy (speed of electrical conduction within the heart).
Beta 1 stimulation affects 1 heart.
Photo by jesse orrico
Beta 2 stimulation causes smooth muscle relaxation, skeletal muscle vasodilation, bronchodilation, and stabilisation of mast cell membranes, reducing histamine release.
Beta 2 stimulation improves airflow to 2 lungs.
